Enantioselective synthesis of indole derivativesIndole, and structures derived from it, are a component of many natural substances, such as the amino acid tryptophan. A new catalytic reaction produces cyclopenta[b]indoles -- frameworks made of three rings that are joined at the edges -- very selectively and with the desired spatial structure. The rates of the different steps of the reaction play a critical role.
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Enantioselective synthesis of indole derivatives#news